3-Nitroacetophenone (CAS 121-89-1) Supplier: S.Nihar Exports
3-Nitroacetophenone: Chemical Profile and Properties
3-Nitroacetophenone (m-nitroacetophenone, CAS 121-89-1) is a pale yellow crystalline solid with 99% purity. It has a molecular formula of C8H7NO3 and a molecular weight of 165.15 g/mol. This fine chemical is classified as a pharmaceutical intermediate.
Key Applications in Pharmaceutical Synthesis
As a pharmaceutical intermediate, 3-Nitroacetophenone is a key component in the synthesis of meta-substituted aniline derivatives, achieved via selective nitro reduction. It serves as a precursor to 3-aminoacetophenone, a pharmaceutical building block for anti-asthmatic and anti-inflammatory active pharmaceutical ingredients (APIs). In medicinal chemistry, 3-Nitroacetophenone is employed in Knoevenagel condensations and Meerwein arylation reactions.
Broader Industrial Applications
Beyond pharmaceutical uses, 3-Nitroacetophenone functions as a substrate for Knoevenagel condensations, leading to the synthesis of chalcones and flavones. It is also utilized as a dye intermediate and as a building block in agrochemical synthesis.
Sourcing 3-Nitroacetophenone from S.Nihar Exports
S.Nihar Exports, an ISO 9001:2015 certified fine and specialty chemical supplier, offers 3-Nitroacetophenone (CAS 121-89-1) globally. The company is headquartered at 512 Maker Bhavan 3, New Marine Lines, Mumbai 400020, India. Founded in 1995, S.Nihar Exports is part of N. Himatlal & Co. A Certificate of Analysis (COA) is provided with every shipment of 3-Nitroacetophenone. In addition to the standard 99% purity, HPLC-grade, ACS reagent, and indicator-grade variants of 3-Nitroacetophenone are available upon request.